Oligoribonuclease Contributes to Tolerance to Aminoglycoside and β-Lactam Antibiotics by Regulating KatA in Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic bacterial pathogen and is intrinsically resistant to a variety of antibiotics. Oligoribonuclease (Orn) is a 3′-to-5′ exonuclease that degrades nanoRNAs. The Orn controls biofilm formation by influencing the homeostasis of cyclic-di-GMP. Previously, we demon...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Xia, Bin, Li, Mei, Tian, Zhenyang, Chen, Gukui, Liu, Chang, Xia, Yushan, Jin, Yongxin, Bai, Fang, Cheng, Zhihui, Jin, Shouguang, Wu, Weihui
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535506/
https://ncbi.nlm.nih.gov/pubmed/30936107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00212-19
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