TpiA is a Key Metabolic Enzyme That Affects Virulence and Resistance to Aminoglycoside Antibiotics through CrcZ in Pseudomonas aeruginosa

Carbon metabolism plays an essential role in bacterial pathogenesis and susceptibility to antibiotics. In Pseudomonas aeruginosa, Crc, Hfq, and a small RNA, CrcZ, are central regulators of carbon metabolism. By screening mutants of genes involved in carbon metabolism, we found that mutation of the t...

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Veröffentlicht in:mBio
Hauptverfasser: Xia, Yushan, Wang, Dan, Pan, Xiaolei, Xia, Bin, Weng, Yuding, Long, Yuqing, Ren, Huan, Zhou, Jingyi, Jin, Yongxin, Bai, Fang, Cheng, Zhihui, Jin, Shouguang, Wu, Weihui
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946797/
https://ncbi.nlm.nih.gov/pubmed/31911486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02079-19
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