Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells

The spatial organization of chromatin is pivotal for regulating genome functions. We report an imaging method for tracing chromatin organization with kilobase- and nanometer-scale resolution, unveiling chromatin conformation across topologically associating domains (TADs) in thousands of individual...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Science
Hoofdauteurs: Bintu, Bogdan, Mateo, Leslie J., Su, Jun-Han, Sinnott-Armstrong, Nicholas A., Parker, Mirae, Kinrot, Seon, Yamaya, Kei, Boettiger, Alistair N., Zhuang, Xiaowei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535145/
https://ncbi.nlm.nih.gov/pubmed/30361340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau1783
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items