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Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells

The spatial organization of chromatin is pivotal for regulating genome functions. We report an imaging method for tracing chromatin organization with kilobase- and nanometer-scale resolution, unveiling chromatin conformation across topologically associating domains (TADs) in thousands of individual...

詳細記述

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書誌詳細
出版年:Science
主要な著者: Bintu, Bogdan, Mateo, Leslie J., Su, Jun-Han, Sinnott-Armstrong, Nicholas A., Parker, Mirae, Kinrot, Seon, Yamaya, Kei, Boettiger, Alistair N., Zhuang, Xiaowei
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535145/
https://ncbi.nlm.nih.gov/pubmed/30361340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau1783
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