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Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells
The spatial organization of chromatin is pivotal for regulating genome functions. We report an imaging method for tracing chromatin organization with kilobase- and nanometer-scale resolution, unveiling chromatin conformation across topologically associating domains (TADs) in thousands of individual...
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| Vydáno v: | Science |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535145/ https://ncbi.nlm.nih.gov/pubmed/30361340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau1783 |
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