Derivation of simian tropic HIV-1 infectious clone reveals virus adaptation to a new host

To replicate in a new host, lentiviruses must adapt to exploit required host factors and evade species-specific antiviral proteins. Understanding how host protein variation drives lentivirus adaptation allowed us to expand the host range of HIV-1 to pigtail macaques. We have previously derived a vir...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Schmidt, Fabian, Keele, Brandon F., Del Prete, Gregory Q., Voronin, Dennis, Fennessey, Christine M., Soll, Steven, Kane, Melissa, Raymond, Alice, Gifford, Robert J., KewalRamani, Vineet, Lifson, Jeffrey D., Bieniasz, Paul D., Hatziioannou, Theodora
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2019
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535013/
https://ncbi.nlm.nih.gov/pubmed/31048506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818059116
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