Derivation of simian tropic HIV-1 infectious clone reveals virus adaptation to a new host

To replicate in a new host, lentiviruses must adapt to exploit required host factors and evade species-specific antiviral proteins. Understanding how host protein variation drives lentivirus adaptation allowed us to expand the host range of HIV-1 to pigtail macaques. We have previously derived a vir...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Schmidt, Fabian, Keele, Brandon F., Del Prete, Gregory Q., Voronin, Dennis, Fennessey, Christine M., Soll, Steven, Kane, Melissa, Raymond, Alice, Gifford, Robert J., KewalRamani, Vineet, Lifson, Jeffrey D., Bieniasz, Paul D., Hatziioannou, Theodora
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535013/
https://ncbi.nlm.nih.gov/pubmed/31048506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818059116
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