Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain

Neuropathic pain afflicts millions of individuals and represents a major health problem for which there is limited effective and safe therapy. Emerging literature links altered sphingolipid metabolism to nociceptive processing. However, the neuropharmacology of sphingolipid signaling in the central...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Zhoumou, Doyle, Timothy M., Luongo, Livio, Largent-Milnes, Tally M., Giancotti, Luigino Antonio, Kolar, Grant, Squillace, Silvia, Boccella, Serena, Walker, John K., Pendleton, Alexander, Spiegel, Sarah, Neumann, William L., Vanderah, Todd W., Salvemini, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534990/
https://ncbi.nlm.nih.gov/pubmed/31068460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820466116
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