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Simvastatin protects photoreceptors from oxidative stress induced by all‐trans‐retinal, through the up‐regulation of interphotoreceptor retinoid binding protein

BACKGROUND AND PURPOSE: Simvastatin is a 3‐hydroxy‐3‐methylglutaryl CoA reductase inhibitor with multiple targets and effects. It protects neurons in the brain, but its protective effects on photoreceptors are unclear. In this study, we evaluated the neuroprotective effect of simvastatin on photorec...

詳細記述

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書誌詳細
出版年:Br J Pharmacol
主要な著者: Zhang, Ting, Gillies, Mark, Wang, Ying, Shen, Weiyong, Bahrami, Bobak, Zeng, Shaoxue, Zhu, Meidong, Yao, Wenjuan, Zhou, Fanfan, Murray, Michael, Wang, Ke, Zhu, Ling
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534793/
https://ncbi.nlm.nih.gov/pubmed/30825184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14650
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