Human organic anion transporting polypeptide 1A2 (OATP1A2) mediates cellular uptake of all-trans-retinol in human retinal pigmented epithelial cells

BACKGROUND AND PURPOSE: Vision depends on retinoid exchange between the retinal pigment epithelium (RPE) and photoreceptors. Defects in any step of the canonical visual cycle can lead to retinal degenerations. All-trans-retinol (atROL) plays an important role in visual signal transduction. However,...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Chan, Ting, Zhu, Ling, Madigan, Michele C, Wang, Ke, Shen, Weiyong, Gillies, Mark C, Zhou, Fanfan
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403098/
https://ncbi.nlm.nih.gov/pubmed/25560245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13060
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