Stress-induced tunneling nanotubes support treatment adaptation in prostate cancer

Tunneling nanotubes (TNTs) are actin-based membranous structures bridging distant cells for intercellular communication. We define roles for TNTs in stress adaptation and treatment resistance in prostate cancer (PCa). Androgen receptor (AR) blockade and metabolic stress induce TNTs, but not in norma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kretschmer, Alexander, Zhang, Fan, Somasekharan, Syam Prakash, Tse, Charan, Leachman, Lauren, Gleave, Anna, Li, Brian, Asmaro, Ivan, Huang, Teresa, Kotula, Leszek, Sorensen, Poul H., Gleave, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534589/
https://ncbi.nlm.nih.gov/pubmed/31127190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44346-5
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