Tunneling Nanotubes Mediate Adaptation of Glioblastoma Cells to Temozolomide and Ionizing Radiation Treatment

Glioblastoma (GBM) is the most prevalent and aggressive tumor in the central nervous system. Surgical resection followed by concurrent radiotherapy (ionizing radiation [IR]) and temozolomide (TMZ) is the standard of care for GBM. However, a large subset of patients offer resistance or become adapted...

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Veröffentlicht in:iScience
Hauptverfasser: Valdebenito, Silvana, Audia, Alessandra, Bhat, Krishna P.L., Okafo, George, Eugenin, Eliseo A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476317/
https://ncbi.nlm.nih.gov/pubmed/32882515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101450
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