Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol

The bacterial Cytochrome P450 (CYP) BM3 (CYP102A1) is one of the most active CYP isoforms. BM3 mutants can serve as a model for human drug-metabolizing CYPs and/or as biocatalyst for selective formation of drug metabolites. Hence, molecular and computational biologists have in the last two decades s...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Frydenvang, Karla, Verkade-Vreeker, Marlies C. A., Dohmen, Floor, Commandeur, Jan N. M., Rafiq, Maria, Mirza, Osman, Jørgensen, Flemming Steen, Geerke, Daan P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534296/
https://ncbi.nlm.nih.gov/pubmed/31125381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217292
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