Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cells

Chalcones are valuable structures for drug discovery due to their broad bioactivity spectrum. In this study, we evaluated 20 synthetic chalcones against estrogen-receptor-positive breast cancer cells (MCF-7 line) and triple-negative breast cancer (TNBC) cells (MDA-MB-231 line). Antiproliferative scr...

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Detaylı Bibliyografya
Yayımlandı:J Enzyme Inhib Med Chem
Asıl Yazarlar: dos Santos, Mariana Bastos, Bertholin Anselmo, Daiane, de Oliveira, Jéssica Gisleine, Jardim-Perassi, Bruna V., Alves Monteiro, Diego, Silva, Gabriel, Gomes, Eleni, Lucia Fachin, Ana, Marins, Mozart, de Campos Zuccari, Débora Aparecida Pires, Octavio Regasini, Luis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2019
Konular:
Short Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534249/
https://ncbi.nlm.nih.gov/pubmed/31117836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1615485
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