Chalcone Derivatives 4′-Amino-1-Naphthyl-Chalcone (D14) and 4′-Amino-4-Methyl-1-Naphthyl-Chalcone (D15) Suppress Migration and Invasion of Osteosarcoma Cells Mediated by p53 Regulating EMT-Related Genes

Osteosarcoma (OS) is a primary malignant bone tumor that mainly affects children, adolescents, and young adults. The inhibition of metastasis is a main strategy of OS therapy since the development of metastatic disease due to drug resistance remains the most important cause of death from this cancer...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Seba, Viviane, Silva, Gabriel, dos Santos, Mariana Bastos, Baek, Seung Joon, França, Suzelei de Castro, Fachin, Ana Lúcia, Regasini, Luis Octavio, Marins, Mozart
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163733/
https://ncbi.nlm.nih.gov/pubmed/30235848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092838
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