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The Connexin50D47A Mutant Causes Cataracts by Calcium Precipitation
PURPOSE: Mutations in connexin50 (Cx50) and connexin46 (Cx46) cause cataracts. Because the expression of Cx46fs380 leads to decreased gap junctional coupling and formation of calcium precipitates, we studied Cx50D47A lenses to test whether Cx50 mutants also cause cataracts due to calcium precipitati...
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| Udgivet i: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Association for Research in Vision and Ophthalmology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534014/ https://ncbi.nlm.nih.gov/pubmed/31117126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-26459 |
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