Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT(2C) Receptor

An impaired signaling capacity of the serotonin (5-HT) 5-HT(2C) receptor (5-HT(2C)R) has been implicated in the neurobehavioral processes that promote relapse vulnerability in cocaine use disorder (CUD). Restoration of the diminished 5-HT(2C)R signaling through positive allosteric modulation present...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Wild, Christopher T., Miszkiel, Joanna M., Wold, Eric A., Soto, Claudia A., Ding, Chunyong, Hartley, Rachel M., White, Mark A., Anastasio, Noelle C., Cunningham, Kathryn A., Zhou, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533912/
https://ncbi.nlm.nih.gov/pubmed/29620897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b00401
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