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Synthesis and activity of functionalizable derivatives of the serotonin (5-HT) 5-HT(2A) receptor (5-HT(2A)R) antagonist M100907

The approach of tethering together two known receptor ligands, to be used as molecular probes for the study of G protein-coupled receptor (GPCR) systems, has proven to be a valuable approach. Selective ligands that possess functionality that can be used to link to other ligands, are useful in the de...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Gilbertson, Scott R., Chen, Ying-Chu, Soto, Claudia A., Yang, Yaxing, Rice, Kenner C., Cunningham, Kathryn A., Anastasio, Noelle C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613932/
https://ncbi.nlm.nih.gov/pubmed/29555153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.02.058
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