Elucidation of the Differences in Cinobufotalin’s Pharmacokinetics Between Normal and Diethylnitrosamine-Injured Rats: The Role of P-Glycoprotein

Cinobufotalin is one of the major anti-tumor components isolated from toad venom and has been used in the clinical therapy of hepatocellular carcinoma (HCC), known as Cinobufacini injection. However, the pharmacokinetic (PK) behaviors of cinobufotalin in vivo with HCC are still unknown. Hence, we ha...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Pharmacol
Egile Nagusiak: Zhang, Xiaojing, Liu, Tong, Zhang, Yidan, Liu, Fanye, Li, Haiying, Fang, Dong, Wang, Chaojie, Sun, Hua, Xie, Songqiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533572/
https://ncbi.nlm.nih.gov/pubmed/31156437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00521
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