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HoxA9 binds and represses the Cebpa +8 kb enhancer
C/EBPα plays a key role in specifying myeloid lineage development. HoxA9 is expressed in myeloid progenitors, with its level diminishing during myeloid maturation, and HOXA9 is over-expressed in a majority of acute myeloid leukemia cases, including those expressing NUP98-HOXD13. The objective of thi...
Enregistré dans:
| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6532930/ https://ncbi.nlm.nih.gov/pubmed/31120998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217604 |
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