HoxA9 binds and represses the Cebpa +8 kb enhancer

C/EBPα plays a key role in specifying myeloid lineage development. HoxA9 is expressed in myeloid progenitors, with its level diminishing during myeloid maturation, and HOXA9 is over-expressed in a majority of acute myeloid leukemia cases, including those expressing NUP98-HOXD13. The objective of thi...

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Udgivet i:PLoS One
Main Authors: Peng, Lei, Guo, Hong, Ma, Peilin, Sun, Yuqing, Dennison, Lauren, Aplan, Peter D., Hess, Jay L., Friedman, Alan D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532930/
https://ncbi.nlm.nih.gov/pubmed/31120998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217604
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