Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone

Bone metastases are prevalent in many common cancers such as breast, prostate, and lung cancers, and novel therapies for treating bone metastases are needed. Human immune system-engrafted models are used in immuno-oncology (IO) studies for subcutaneous cancer cell or patient-derived xenograft implan...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Kähkönen, Tiina E., Suominen, Mari I., Mäki-Jouppila, Jenni H. E., Halleen, Jussi M., Tanaka, Azusa, Seiler, Michael, Bernoulli, Jenni
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532310/
https://ncbi.nlm.nih.gov/pubmed/31211147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4260987
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