Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone

Bone metastases are prevalent in many common cancers such as breast, prostate, and lung cancers, and novel therapies for treating bone metastases are needed. Human immune system-engrafted models are used in immuno-oncology (IO) studies for subcutaneous cancer cell or patient-derived xenograft implan...

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Udgivet i:J Immunol Res
Main Authors: Kähkönen, Tiina E., Suominen, Mari I., Mäki-Jouppila, Jenni H. E., Halleen, Jussi M., Tanaka, Azusa, Seiler, Michael, Bernoulli, Jenni
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532310/
https://ncbi.nlm.nih.gov/pubmed/31211147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4260987
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