Dovitinib dilactic acid reduces tumor growth and tumor-induced bone changes in an experimental breast cancer bone growth model

Advanced breast cancer has a high incidence of bone metastases. In bone, breast cancer cells induce osteolytic or mixed bone lesions by inducing an imbalance in bone formation and resorption. Activated fibroblast growth factor receptors (FGFRs) are important in regulation of tumor growth and bone re...

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Publicat a:J Bone Oncol
Autors principals: Kähkönen, Tiina E., Tuomela, Johanna M., Grönroos, Tove J., Halleen, Jussi M., Ivaska, Kaisa K., Härkönen, Pirkko L.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434100/
https://ncbi.nlm.nih.gov/pubmed/30956945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2019.100232
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