Dovitinib dilactic acid reduces tumor growth and tumor-induced bone changes in an experimental breast cancer bone growth model

Advanced breast cancer has a high incidence of bone metastases. In bone, breast cancer cells induce osteolytic or mixed bone lesions by inducing an imbalance in bone formation and resorption. Activated fibroblast growth factor receptors (FGFRs) are important in regulation of tumor growth and bone re...

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Detalles Bibliográficos
Publicado en:J Bone Oncol
Autores principales: Kähkönen, Tiina E., Tuomela, Johanna M., Grönroos, Tove J., Halleen, Jussi M., Ivaska, Kaisa K., Härkönen, Pirkko L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434100/
https://ncbi.nlm.nih.gov/pubmed/30956945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2019.100232
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