Curcumin suppresses epithelial-to-mesenchymal transition of peritoneal mesothelial cells (HMrSV5) through regulation of transforming growth factor-activated kinase 1 (TAK1)

OBJECTIVE: Peritoneal fibrosis remains a serious complication of long-term peritoneal dialysis (PD) leading to peritoneal membrane ultrafiltration failure. Epithelial–mesenchymal transition (EMT) of peritoneal mesothelial cells (PMCs) is a key process of peritoneal fibrosis. Curcumin has been previo...

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Udgivet i:Cell Mol Biol Lett
Main Authors: Zhao, Jun-Li, Guo, Mei-Zi, Zhu, Jun-Jun, Zhang, Ting, Min, Dan-Yan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532179/
https://ncbi.nlm.nih.gov/pubmed/31143210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-019-0157-x
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