Asiaticoside inhibits TGF-β1-induced mesothelial-mesenchymal transition and oxidative stress via the Nrf2/HO-1 signaling pathway in the human peritoneal mesothelial cell line HMrSV5

BACKGROUND: Peritoneal fibrosis (PF) is a frequent complication caused by peritoneal dialysis (PD). Peritoneal mesothelial cells (PMCs), the first barrier of the peritoneum, play an important role in maintaining structure and function in the peritoneum during PD. Mesothelial-mesenchymal transition (...

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Gepubliceerd in:Cell Mol Biol Lett
Hoofdauteurs: Zhao, Junyi, Shi, Jun, Shan, Yun, Yu, Manshu, Zhu, Xiaolin, Zhu, Yilin, Liu, Li, Sheng, Meixiao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257216/
https://ncbi.nlm.nih.gov/pubmed/32514269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-020-00226-9
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