Asiaticoside inhibits TGF-β1-induced mesothelial-mesenchymal transition and oxidative stress via the Nrf2/HO-1 signaling pathway in the human peritoneal mesothelial cell line HMrSV5

BACKGROUND: Peritoneal fibrosis (PF) is a frequent complication caused by peritoneal dialysis (PD). Peritoneal mesothelial cells (PMCs), the first barrier of the peritoneum, play an important role in maintaining structure and function in the peritoneum during PD. Mesothelial-mesenchymal transition (...

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Bibliografiske detaljer
Udgivet i:Cell Mol Biol Lett
Main Authors: Zhao, Junyi, Shi, Jun, Shan, Yun, Yu, Manshu, Zhu, Xiaolin, Zhu, Yilin, Liu, Li, Sheng, Meixiao
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257216/
https://ncbi.nlm.nih.gov/pubmed/32514269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-020-00226-9
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