Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells

BACKGROUND: We investigated the effects of tranilast on epithelial-to-mesenchymal transition (EMT) in an animal model and on the EMT signaling pathway in human peritoneal mesothelial cells (HPMCs). METHODS: We performed in vitro studies (cytotoxicity, cell morphology, and western blot analyses) on H...

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Pubblicato in:Kidney Res Clin Pract
Autori principali: Kang, Seok Hui, Kim, Sang Woon, Kim, Keuk Jun, Cho, Kyu Hyang, Park, Jong Won, Kim, Chan-Duck, Do, Jun Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society of Nephrology 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913598/
https://ncbi.nlm.nih.gov/pubmed/31554027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.23876/j.krcp.19.049
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