Modulation of Sialic Acid Dependence Influences the Central Nervous System Transduction Profile of Adeno-associated Viruses

Central nervous system (CNS) transduction by systemically administered recombinant adeno-associated viral (AAV) vectors requires crossing the blood-brain barrier (BBB). We recently mapped a structural footprint on the AAVrh.10 capsid, which, when grafted onto the AAV1 capsid (AAV1RX), enables viral...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Albright, Blake H., Simon, Katherine E., Pillai, Minakshi, Devlin, Garth W., Asokan, Aravind
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Virus-Cell Interactions
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532073/
https://ncbi.nlm.nih.gov/pubmed/30894463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00332-19
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller