Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

Cyclic AMP (cAMP) is an important signalling molecule across evolution, but its role in malaria parasites is poorly understood. We have investigated the role of cAMP in asexual blood stage development of Plasmodium falciparum through conditional disruption of adenylyl cyclase beta (ACβ) and its down...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Patel, Avnish, Perrin, Abigail J., Flynn, Helen R., Bisson, Claudine, Withers-Martinez, Chrislaine, Treeck, Moritz, Flueck, Christian, Nicastro, Giuseppe, Martin, Stephen R., Ramos, Andres, Gilberger, Tim W., Snijders, Ambrosius P., Blackman, Michael J., Baker, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530879/
https://ncbi.nlm.nih.gov/pubmed/31075098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000264
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