Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion

Cyclic nucleotide signalling is a major regulator of malaria parasite differentiation. Phosphodiesterase (PDE) enzymes are known to control cyclic GMP (cGMP) levels in the parasite, but the mechanisms by which cyclic AMP (cAMP) is regulated remain enigmatic. Here, we demonstrate that Plasmodium falc...

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Библиографические подробности
Опубликовано в: :PLoS Biol
Главные авторы: Flueck, Christian, Drought, Laura G., Jones, Andrew, Patel, Avnish, Perrin, Abigail J., Walker, Eloise M., Nofal, Stephanie D., Snijders, Ambrosius P., Blackman, Michael J., Baker, David A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402698/
https://ncbi.nlm.nih.gov/pubmed/30794532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000154
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