Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion

Cyclic nucleotide signalling is a major regulator of malaria parasite differentiation. Phosphodiesterase (PDE) enzymes are known to control cyclic GMP (cGMP) levels in the parasite, but the mechanisms by which cyclic AMP (cAMP) is regulated remain enigmatic. Here, we demonstrate that Plasmodium falc...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Flueck, Christian, Drought, Laura G., Jones, Andrew, Patel, Avnish, Perrin, Abigail J., Walker, Eloise M., Nofal, Stephanie D., Snijders, Ambrosius P., Blackman, Michael J., Baker, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402698/
https://ncbi.nlm.nih.gov/pubmed/30794532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000154
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