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Alagille Syndrome: A Novel Mutation in JAG1 Gene

Alagille syndrome is an autosomal dominant multisystem disorder with variable phenotypic penetrance, caused by heterozygous mutations in JAG1 or NOTCH2, encoding for the components of the Notch signaling pathway. In this paper, we described a novel mutation not yet reported in literature. This 3-yea...

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Detalhes bibliográficos
Publicado no:Front Pediatr
Main Authors: Fischetto, Rita, Palmieri, Viviana V., Tripaldi, Maria E., Gaeta, Alberto, Michelucci, Angela, Delvecchio, Maurizio, Francavilla, Ruggiero, Giordano, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529843/
https://ncbi.nlm.nih.gov/pubmed/31157196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2019.00199
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