Uptake of Sialic Acid by Nontypeable Haemophilus influenzae Increases Complement Resistance through Decreasing IgM-Dependent Complement Activation

Although nontypeable Haemophilus influenzae (NTHi) is a human-specific nasopharyngeal commensal bacterium, it also causes upper respiratory tract infections in children and lower respiratory tract infections in the elderly, resulting in frequent antibiotic use. The transition from symbiotic colonizi...

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Udgivet i:Infect Immun
Main Authors: Oerlemans, Marjolein M. P., Moons, Sam J., Heming, Jurriaan J. A., Boltje, Thomas J., de Jonge, Marien I., Langereis, Jeroen D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529651/
https://ncbi.nlm.nih.gov/pubmed/30936154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00077-19
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