Nontypeable Haemophilus influenzae Invasive Blood Isolates Are Mainly Phosphorylcholine Negative and Show Decreased Complement-Mediated Killing That Is Associated with Lower Binding of IgM and CRP in Comparison to Colonizing Isolates from the Oropharynx

Nontypeable Haemophilus influenzae (NTHi) bacteria express various molecules that contribute to their virulence. The presence of phosphocholine (PCho) on NTHi lipooligosaccharide increases adhesion to epithelial cells and is an advantage for the bacterium, enabling nasopharyngeal colonization, as me...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Langereis, Jeroen D., Cremers, Amelieke J. H., Vissers, Marloes, van Beek, Josine, Meis, Jacques F., de Jonge, Marien I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346125/
https://ncbi.nlm.nih.gov/pubmed/30455196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00604-18
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