Nontypeable Haemophilus influenzae Invasive Blood Isolates Are Mainly Phosphorylcholine Negative and Show Decreased Complement-Mediated Killing That Is Associated with Lower Binding of IgM and CRP in Comparison to Colonizing Isolates from the Oropharynx

Nontypeable Haemophilus influenzae (NTHi) bacteria express various molecules that contribute to their virulence. The presence of phosphocholine (PCho) on NTHi lipooligosaccharide increases adhesion to epithelial cells and is an advantage for the bacterium, enabling nasopharyngeal colonization, as me...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Infect Immun
Prif Awduron: Langereis, Jeroen D., Cremers, Amelieke J. H., Vissers, Marloes, van Beek, Josine, Meis, Jacques F., de Jonge, Marien I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2019
Pynciau:
Molecular Pathogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346125/
https://ncbi.nlm.nih.gov/pubmed/30455196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00604-18
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