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Uptake of Sialic Acid by Nontypeable Haemophilus influenzae Increases Complement Resistance through Decreasing IgM-Dependent Complement Activation

Although nontypeable Haemophilus influenzae (NTHi) is a human-specific nasopharyngeal commensal bacterium, it also causes upper respiratory tract infections in children and lower respiratory tract infections in the elderly, resulting in frequent antibiotic use. The transition from symbiotic colonizi...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Oerlemans, Marjolein M. P., Moons, Sam J., Heming, Jurriaan J. A., Boltje, Thomas J., de Jonge, Marien I., Langereis, Jeroen D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529651/
https://ncbi.nlm.nih.gov/pubmed/30936154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00077-19
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