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SLAP Is a Negative Regulator of FcεRI Receptor-Mediated Signaling and Allergic Response
Binding of antigen to IgE-high affinity FcεRI complexes on mast cells and basophils results in the release of preformed mediators such as histamine and de novo synthesis of cytokines causing allergic reactions. Src-like adapter protein (SLAP) functions co-operatively with c-Cbl to negatively regulat...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6529641/ https://ncbi.nlm.nih.gov/pubmed/31156621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01020 |
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