Inhibiting Bone Morphogenetic Protein 4 Type I Receptor Signaling Promotes Remyelination by Potentiating Oligodendrocyte Differentiation

Blocking inhibitory factors within CNS demyelinating lesions is regarded as a promising strategy to promote remyelination. Bone morphogenetic protein 4 (BMP4) is an inhibitory factor present in demyelinating lesions. Noggin, an endogenous antagonist to BMP, has previously been shown to increase the...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:eNeuro
Hlavní autoři: Govier-Cole, Alistair E., Wood, Rhiannon J., Fletcher, Jessica L., Gonsalvez, David G., Merlo, Daniel, Cate, Holly S., Murray, Simon S., Xiao, Junhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2019
Témata:
New Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529590/
https://ncbi.nlm.nih.gov/pubmed/31028086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0399-18.2019
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky