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The mechanistic target of rapamycin pathway downregulates bone morphogenetic protein signaling to promote oligodendrocyte differentiation

Oligodendrocyte precursor cells (OPCs) differentiate and mature into oligodendrocytes, which produce myelin in the central nervous system. Prior studies have shown that the mechanistic target of rapamycin (mTOR) is necessary for proper myelination of the mouse spinal cord and that bone morphogenetic...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Ornelas, Isis M., Khandker, Luipa, Wahl, Stacey E., Hashimoto, Hirokazu, Macklin, Wendy B., Wood, Teresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368967/
https://ncbi.nlm.nih.gov/pubmed/31904150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23776
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