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PAK1 Positively Regulates Oligodendrocyte Morphology and Myelination
The actin cytoskeleton is crucial for oligodendrocyte differentiation and myelination. Here we show that p21-activated kinase 1 (PAK1), a well-known actin regulator, promotes oligodendrocyte morphologic change and myelin production in the CNS. A combination of in vitro and in vivo models demonstrate...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7939082/ https://ncbi.nlm.nih.gov/pubmed/33478987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0229-20.2021 |
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