The Protein Tyrosine Phosphatase Shp2 Regulates Oligodendrocyte Differentiation and Early Myelination and Contributes to Timely Remyelination

Shp2 is a nonreceptor protein tyrosine phosphatase that has been shown to influence neurogenesis, oligodendrogenesis, and oligodendrocyte differentiation. Furthermore, Shp2 is a known regulator of the Akt/mammalian target of rapamycin and ERK signaling pathways in multiple cellular contexts, includi...

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Publicado en:J Neurosci
Autores principales: Ahrendsen, Jared T., Harlow, Danielle E., Finseth, Lisbet T., Bourne, Jennifer N., Hickey, Sean P., Gould, Elizabeth A., Culp, Cecilia M., Macklin, Wendy B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2018
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783963/
https://ncbi.nlm.nih.gov/pubmed/29217681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2864-16.2017
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