Differential Modulation of the Oligodendrocyte Transcriptome by Sonic Hedgehog and Bone Morphogenetic Protein 4 via Opposing Effects on Histone Acetylation

Differentiation of oligodendrocyte progenitor cells (OPCs) into mature oligodendrocytes is regulated by the interplay between extrinsic signals and intrinsic epigenetic determinants. In this study, we analyze the effect that the extracellular ligands sonic hedgehog (Shh) and bone morphogenetic prote...

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Detalhes bibliográficos
Main Authors: Wu, Muzhou, Hernandez, Marylens, Shen, Siming, Sabo, Jennifer K., Kelkar, Dipti, Wang, Ju, O'Leary, Robert, Phillips, Greg R., Cate, Holly S., Casaccia, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412138/
https://ncbi.nlm.nih.gov/pubmed/22573687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4876-11.2012
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