Whole-Exome Sequencing Identifies Somatic Mutations Associated With Mortality in Metastatic Clear Cell Kidney Carcinoma

Clear cell renal cell carcinoma (ccRCC) is among the most aggressive histologic subtypes of kidney cancer, representing about 3% of all human cancers. Patients at stage IV have nearly 60% of mortality in 2–3 years after diagnosis. To date, most ccRCC studies have used DNA microarrays and targeted se...

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Detalles Bibliográficos
Publicado en:Front Genet
Autores principales: Mendoza-Alvarez, Alejandro, Guillen-Guio, Beatriz, Baez-Ortega, Adrian, Hernandez-Perez, Carolina, Lakhwani-Lakhwani, Sita, Maeso, Maria-del-Carmen, Lorenzo-Salazar, Jose M., Morales, Manuel, Flores, Carlos
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529576/
https://ncbi.nlm.nih.gov/pubmed/31156702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00439
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