Whole-Exome Sequencing Identifies Somatic Mutations Associated With Mortality in Metastatic Clear Cell Kidney Carcinoma

Clear cell renal cell carcinoma (ccRCC) is among the most aggressive histologic subtypes of kidney cancer, representing about 3% of all human cancers. Patients at stage IV have nearly 60% of mortality in 2–3 years after diagnosis. To date, most ccRCC studies have used DNA microarrays and targeted se...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Mendoza-Alvarez, Alejandro, Guillen-Guio, Beatriz, Baez-Ortega, Adrian, Hernandez-Perez, Carolina, Lakhwani-Lakhwani, Sita, Maeso, Maria-del-Carmen, Lorenzo-Salazar, Jose M., Morales, Manuel, Flores, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529576/
https://ncbi.nlm.nih.gov/pubmed/31156702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00439
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