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Perturbation of Thymocyte Development Underlies the PRRS Pandemic: A Testable Hypothesis

Porcine reproductive and respiratory syndrome virus (PRRSV) causes immune dysregulation during the Critical Window of Immunological Development. We hypothesize that thymocyte development is altered by infected thymic antigen presenting cells (TAPCs) in the fetal/neonatal thymus that interact with do...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Butler, John E., Sinkora, Marek, Wang, Gang, Stepanova, Katerina, Li, Yuming, Cai, Xuehui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529568/
https://ncbi.nlm.nih.gov/pubmed/31156633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01077
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