Perturbation of Thymocyte Development Underlies the PRRS Pandemic: A Testable Hypothesis

Porcine reproductive and respiratory syndrome virus (PRRSV) causes immune dysregulation during the Critical Window of Immunological Development. We hypothesize that thymocyte development is altered by infected thymic antigen presenting cells (TAPCs) in the fetal/neonatal thymus that interact with do...

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Vydáno v:Front Immunol
Hlavní autoři: Butler, John E., Sinkora, Marek, Wang, Gang, Stepanova, Katerina, Li, Yuming, Cai, Xuehui
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529568/
https://ncbi.nlm.nih.gov/pubmed/31156633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01077
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