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Role of the membrane potential in mitochondrial protein unfolding and import

Newly synthesized mitochondrial precursor proteins have to become unfolded to cross the mitochondrial membranes. This unfolding is achieved primarily by mitochondrial Hsp70 (mtHsp70) for presequence-containing precursor proteins. However, the membrane potential across the inner membrane (ΔΨ) could a...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sato, Takehiro K., Kawano, Shin, Endo, Toshiya
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529458/
https://ncbi.nlm.nih.gov/pubmed/31114030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44152-z
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