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Structural basis for unfolding pathway-dependent stability of proteins: Vectorial unfolding versus global unfolding
Point mutations in proteins can have different effects on protein stability depending on the mechanism of unfolding. In the most interesting case of I27, the Ig-like module of the muscle protein titin, one point mutation (Y9P) yields opposite effects on protein stability during denaturant-induced “g...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867010/ https://ncbi.nlm.nih.gov/pubmed/20095049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.346 |
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