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Structural basis for unfolding pathway-dependent stability of proteins: Vectorial unfolding versus global unfolding

Point mutations in proteins can have different effects on protein stability depending on the mechanism of unfolding. In the most interesting case of I27, the Ig-like module of the muscle protein titin, one point mutation (Y9P) yields opposite effects on protein stability during denaturant-induced “g...

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מידע ביבליוגרפי
Main Authors: Yagawa, Keisuke, Yamano, Koji, Oguro, Takaomi, Maeda, Masahiro, Sato, Takehiro, Momose, Takaki, Kawano, Shin, Endo, Toshiya
פורמט: Artigo
שפה:Inglês
יצא לאור: Wiley Subscription Services, Inc., A Wiley Company 2010
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867010/
https://ncbi.nlm.nih.gov/pubmed/20095049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.346
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