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Role of the membrane potential in mitochondrial protein unfolding and import

Newly synthesized mitochondrial precursor proteins have to become unfolded to cross the mitochondrial membranes. This unfolding is achieved primarily by mitochondrial Hsp70 (mtHsp70) for presequence-containing precursor proteins. However, the membrane potential across the inner membrane (ΔΨ) could a...

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Vydáno v:Sci Rep
Hlavní autoři: Sato, Takehiro K., Kawano, Shin, Endo, Toshiya
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529458/
https://ncbi.nlm.nih.gov/pubmed/31114030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44152-z
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