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Ciliary and cytoskeletal functions of an ancient monooxygenase essential for bioactive amidated peptide synthesis
Many secreted peptides used for cell–cell communication require conversion of a C-terminal glycine to an amide for bioactivity. This reaction is catalyzed only by the integral membrane protein peptidylglycine α-amidating monooxygenase (PAM). PAM has been highly conserved and is found throughout the...
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| Publicado en: | Cell Mol Life Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer International Publishing
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6529398/ https://ncbi.nlm.nih.gov/pubmed/30879092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03065-w |
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