A bioactive peptide amidating enzyme is required for ciliogenesis

The pathways controlling cilium biogenesis in different cell types have not been fully elucidated. We recently identified peptidylglycine α-amidating monooxygenase (PAM), an enzyme required for generating amidated bioactive signaling peptides, in Chlamydomonas and mammalian cilia. Here, we show that...

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Bibliographic Details
Published in:eLife
Main Authors: Kumar, Dhivya, Strenkert, Daniela, Patel-King, Ramila S, Leonard, Michael T, Merchant, Sabeeha S, Mains, Richard E, King, Stephen M, Eipper, Betty A
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2017
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461114/
https://ncbi.nlm.nih.gov/pubmed/28513435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25728
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